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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950257Generated: October 31, 2026

4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride → HCID 66627904, compound

https://huagongshe.com/reaction/1950257

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Azepan-1-ylethoxy)benzoic acid hydrochlorideHCID 13174870—
Reactant2-(2-Methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenylamineHCID 57934283—
ReactantHCID 66627967HCID 66627967—
ProductHCID 66627904HCID 66627904—

Reaction Steps

Synthesized from 2-(2-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenylamine and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 152, [4-(2-azepan-1-ylethoxy)benzyl][2-(2-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenyl]amine (477 mg) was used according to an analogous synthetic method to Example 36 to provide [4-(2-azepan-1-ylethoxy)benzyl]ethyl[2-(2-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenyl]amine (431 mg). This compound (429 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (371 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-f398078e887f46c08ec5f515c52c88c1
Source noteuspto-grants-2013_03