HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride → HCID 66627904, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride | HCID 13174870 | — |
| Reactant | 2-(2-Methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenylamine | HCID 57934283 | — |
| Reactant | HCID 66627967 | HCID 66627967 | — |
| Product | HCID 66627904 | HCID 66627904 | — |
Reaction Steps
Synthesized from 2-(2-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenylamine and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 152, [4-(2-azepan-1-ylethoxy)benzyl][2-(2-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenyl]amine (477 mg) was used according to an analogous synthetic method to Example 36 to provide [4-(2-azepan-1-ylethoxy)benzyl]ethyl[2-(2-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenyl]amine (431 mg). This compound (429 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (371 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-f398078e887f46c08ec5f515c52c88c1 |
| Source note | uspto-grants-2013_03 |