HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride → HCID 66627333, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride | HCID 13174870 | — |
| Reactant | {2-[2-(tert-Butyldimethylsilyloxy)-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl]-5-methoxyphenyl}ethylamine | HCID 66626847 | — |
| Reactant | HCID 66627027 | HCID 66627027 | — |
| Product | HCID 66627333 | HCID 66627333 | — |
Reaction Steps
Synthesized from {2-[2-(tert-butyldimethylsilyloxy)-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl]-5-methoxyphenyl}ethylamine and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 152, [4-(2-azepan-1-ylethoxy)benzyl]{2-[2-(tert-butyldimethyl silyloxy)-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl]-5-methoxyphenyl}ethylamine (584 mg) was used according to an analogous synthetic method to Example 325 described below to provide the title compound (426 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-3c47ed2eae34443cb39f0712dde0c304 |
| Source note | uspto-grants-2013_03 |