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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950265Generated: October 30, 2026

HCID 23087231, compound → HCID 66625602, compound

https://huagongshe.com/reaction/1950265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23087231HCID 23087231—
Reactant3-Fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochlorideHCID 66626827—
ReactantHCID 66627351HCID 66627351—
ProductHCID 66625602HCID 66625602—

Reaction Steps

Synthesized from 5-methoxy-2-(6-methoxy-1,1-dimethyl-1,4-dihydronaphthalen-2-yl)phenylamine and 3-fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 114, [3-fluoro-4-(2-piperidin-1-ylethoxy)benzyl][5-methoxy-2-(6-methoxy-1,1-dimethyl-1,4-dihydronaphthalen-2-yl)phenyl]amine (316 mg) was used according to an analogous synthetic method to Example 36 to provide ethyl[3-fluoro-4-(2-piperidin-1-ylethoxy)benzyl][5-methoxy-2-(6-methoxy-1,1-dimethyl-1,4-dihydronaphthalen-2-yl)phenyl]amine (82 mg). The total amount of this compound was used according to an analogous synthetic method to Example 111 to provide the title compound (62 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-b7fcb1e1043c48efa945726343b16e43
Source noteuspto-grants-2013_03