HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → HCID 57934199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine | HCID 23087072 | — |
| Reactant | HCID 23087237 | HCID 23087237 | — |
| Reactant | [3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl][5-methoxy-2-(6-methoxy-1-methyl-1H-indol-2-yl)phenyl]amine | HCID 66627192 | — |
| Product | HCID 57934199 | HCID 57934199 | 44.1% |
Reaction Steps
Synthesized from 5-methoxy-2-(6-methoxy-1-methyl-1H-indol-2-yl)phenylamine and 1-[2-(4-bromo-2-fluorophenoxy)ethyl]piperidine according to an analogous synthetic method to Example 116, [3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl][5-methoxy-2-(6-methoxy-1-methyl-1H-indol-2-yl)phenyl]amine (60 mg) was used according to an analogous synthetic method to Example 364 described below to provide the title compound (25 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-1ba8229235334fa2b9f1c765df2baf7b |
| Source note | uspto-grants-2013_03 |