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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950276Generated: October 30, 2026

1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → HCID 57933745, compound

https://huagongshe.com/reaction/1950276

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidineHCID 23087072—
ReactantHCID 23087092HCID 23087092—
ReactantHCID 23087329HCID 23087329—
ProductHCID 57933745HCID 5793374546.4%

Reaction Steps

Synthesized from 5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenylamine and 1-[2-(4-bromo-2-fluorophenoxy)ethyl]piperidine according to an analogous synthetic method to Example 116, [3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl][5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenyl]amine (322 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (141 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-64716a97a9224dbb8b61d130c9b5a8d7
Source noteuspto-grants-2013_03