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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950278Generated: November 1, 2026

HCID 23087164, compound → HCID 23087081, compound

https://huagongshe.com/reaction/1950278

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23087164HCID 23087164—
ReactantHCID 23087329HCID 23087329—
Reactant3-Fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochlorideHCID 66626827—
ProductHCID 23087081HCID 23087081—

Reaction Steps

Synthesized from 5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenylamine and 3-fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 114, [3-fluoro-4-(2-piperidin-1-ylethoxy)benzyl][5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenyl]amine (231 mg) was used according to an analogous synthetic method to Example 36 to provide ethyl[3-fluoro-4-(2-piperidin-1-ylethoxy)benzyl][5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenyl]amine (195 mg). The total amount of this compound was used according to an analogous synthetic method to Example 111 to provide the title compound (170 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-8db468104b9247d3b7f3b5272f25057c
Source noteuspto-grants-2013_03