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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950286Generated: October 30, 2026

4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride → HCID 66626790, compound

https://huagongshe.com/reaction/1950286

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Azepan-1-ylethoxy)benzoic acid hydrochlorideHCID 13174870—
ReactantHCID 57934104HCID 57934104—
ReactantHCID 66627910HCID 66627910—
ProductHCID 66626790HCID 66626790—

Reaction Steps

Synthesized from 2-[1-(3-methoxyphenyl)pyrrolidin-3-yl]phenylamine and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride according to an analogous method to Example 152, synthetic [4-(2-azepan-1-ylethoxy)benzyl]{2-[1-(3-methoxyphenyl)pyrrolidin-3-yl]phenyl}amine (180 mg) was used according to an analogous synthetic method to Example 36 to provide [4-(2-azepan-1-ylethoxy)benzyl]ethyl {2-[1-(3-methoxyphenyl)pyrrolidin-3-yl]phenyl}amine (153 mg). The total amount of this compound was used according to an analogous synthetic method to Example 111 to provide the title compound (140 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-f3ffcf0547e040d98161ceaada6a3e98
Source noteuspto-grants-2013_03