HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 45081166, compound → HCID 66628190, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 45081166 | HCID 45081166 | — |
| Reactant | Pivalic acid 6-{2-[(3-fluoro-4-hydroxybenzoyl)methylamino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester | HCID 66626888 | — |
| Product | HCID 66628190 | HCID 66628190 | 52.4% |
Reaction Steps
Synthesized from pivalic acid 6-{2-[(3-fluoro-4-hydroxybenzoyl)methylamino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (20 mg) and 1-(7-azabicyclo[2.2.1]hept-7-yl)-2-bromoethanone (17 mg) according to an analogous synthetic method to Example 404 and purified by LC-MS, the title compound (11 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-38fe2ce114a44302b075159ff8552ca5 |
| Source note | uspto-grants-2013_03 |