HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Azabicyclo(3.2.2)nonane, 3-(chloroacetyl)- → HCID 66625559, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Azabicyclo(3.2.2)nonane, 3-(chloroacetyl)- | HCID 14331 | — |
| Reactant | Pivalic acid 6-{2-[(4-hydroxybenzoyl)propylamino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester | HCID 66626482 | — |
| Product | HCID 66625559 | HCID 66625559 | 41.9% |
Reaction Steps
Synthesized from pivalic acid 6-{2-[(4-hydroxybenzoyl)propylamino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (21 mg) and 1-(3-azabicyclo[3.2.2]non-3-yl)-2-chloroethanone (17 mg) according to an analogous synthetic method to Example 404 and purified by LC-MS, the title compound (9.7 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-657f3fac694d4bf6b20cd1a132d3b54c |
| Source note | uspto-grants-2013_03 |