HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-N-(2-fluoroethyl)acetamide → HCID 57934260, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-N-(2-fluoroethyl)acetamide | HCID 23087078 | — |
| Reactant | Pivalic acid 6-{2-[(3-fluoro-4-hydroxybenzoyl)isopropylamino]-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-yl ester | HCID 57934527 | — |
| Product | HCID 57934260 | HCID 57934260 | 22.7% |
Reaction Steps
Synthesized from pivalic acid 6-{2-[(3-fluoro-4-hydroxybenzoyl)isopropylamino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (26 mg) and 2-chloro-N-(2-fluoroethyl)acetamide (14 mg) according to an analogous synthetic method to Example 567 and purified by LC-MS, the title compound (5.8 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-da13753483da4a188f36f891cf0ab997 |
| Source note | uspto-grants-2013_03 |