HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11417530, compound → HCID 57934019, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11417530 | HCID 11417530 | — |
| Reactant | N-(2-chloroethyl)perhydroazepine hydrochloride | HCID 24188283 | — |
| Reactant | HCID 66627807 | HCID 66627807 | — |
| Product | HCID 57934019 | HCID 57934019 | 35.6% |
Reaction Steps
Synthesized from 4-[3-methoxy-7-(4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-1-yloxy]phenol and 1-(2-chloroethyl)azepane hydrochloride according to an analogous synthetic method to Preparation Example 40, 1-{2-{4-[3-methoxy-7-(4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-1-yloxy]phenoxy}ethyl}azepane (345 mg) was used according to an analogous synthetic method to Example 779 described below to provide the title compound (116 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-412ad33a4e1d43de94df3d08e7ac8d1f |
| Source note | uspto-grants-2013_03 |