HCID 11209223, compound → HCID 11358127, compound

HRID 1950610Notes

Reaction equation

HRID 1950610 reaction equation
C[O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11](=O)[C:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)([CH3:14])[CH3:13].OC1C=C(OC)C=CC=1C(=O)C(C1C=CC(OC)=CC=1)(C)C>>[CH3:10][O:9][C:7]1[CH:6]=[CH:5][C:4]([CH2:11][C:12]([C:15]2[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=2)([CH3:14])[CH3:13])=[C:3]([OH:2])[CH:8]=1

Participants

3

Reactant 2

HCID 11209223HCID 11209223, compoundHCID 11771029HCID 11771029, compound

Product 1

HCID 11358127HCID 11358127, compound

Procedure

Synthesized from 1-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)-2-methylpropan-1-one according to an analogous synthetic method to Preparation Example 192 described below, 1-(2-hydroxy-4-methoxyphenyl)-2-(4-methoxyphenyl)-2-methylpropan-1-one (2.9 g) was used according to an analogous synthetic method to Preparation Example 185 described below to provide the title compound (1.9 g).

Workup

  1. customwas used according to an analogous synthetic method to Preparation Example 185

Sources & evidence

ORD record
ord-13bd5116882b4a91becdd3aade2e85c8
Source dataset
uspto-grants-2013_03
Patent number
US08399520B2

Reaction notes

Loading…