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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950625Generated: October 31, 2026

Piperidine, 1-(2-chloroethyl)-, hydrochloride → HCID 11750430, compound

https://huagongshe.com/reaction/1950625

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidine, 1-(2-chloroethyl)-, hydrochlorideHCID 74826—
ReactantHCID 11450457HCID 11450457—
ReactantHCID 23087494HCID 23087494—
ProductHCID 11750430HCID 1175043041.8%

Reaction Steps

Synthesized from 5′-methoxy-2′-[2-(4-methoxyphenyl)ethyl]biphenyl-4-ol and 1-(2-chloroethyl)piperidine hydrochloride according to an analogous synthetic method to Preparation Example 40, 1-{2-{5′-methoxy-2′-[2-(4-methoxyphenyl)ethyl]biphenyl-4-yloxy}ethyl}piperidine (250 mg) was used according to an analogous synthetic method to Example 779 to provide the title compound (98 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-bd301b78583b4a008c8c97f0e4b54688
Source noteuspto-grants-2013_03