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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950643Generated: October 29, 2026

4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester → HCID 57933809, compound

https://huagongshe.com/reaction/1950643

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl esterHCID 22492859—
ReactantHCID 57934515HCID 57934515—
ProductHCID 57933809HCID 57933809102.8%

Reaction Steps

Synthesized from pivalic acid (S)-6-[2-(ethoxycarbonylmethylamino)-4-methoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-yl ester (35 mg) and 4-(4-carboxyphenyl)piperidine-1-carboxylic acid tert-butyl ester (73 mg) according to an analogous synthesis method to the above-mentioned Preparation Example 86 and Example 337, the title compound (41 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-004a539a12764a1987c248829802d711
Source noteuspto-grants-2013_03