HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57934253, compound → HCID 57934173, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57934253 | HCID 57934253 | — |
| Reactant | HCID 66625977 | HCID 66625977 | — |
| Reactant | HCID 66627376 | HCID 66627376 | — |
| Product | HCID 57934173 | HCID 57934173 | 37.7% |
Reaction Steps
Synthesized from pivalic acid (R)-6-(2-ethylamino-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-yl ester (100 mg) and 4-[2-(tert-butoxycarbonylethylamino)-2-methylpropyl]benzoic acid (125 mg) according to an analogous synthetic method to Preparation Example 86, pivalic acid 6-{2-{{4-[2-(tert-butoxycarbonylethylamino)-2-methylpropyl]benzoyl}ethylamino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (69 mg) was used according to an analogous synthetic method to Example 337 to provide the title compound (19 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-d8418ad741174f9d9fb4f9b68de13d88 |
| Source note | uspto-grants-2013_03 |