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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950651Generated: October 31, 2026

4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester → HCID 57934525, compound

https://huagongshe.com/reaction/1950651

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl esterHCID 22492859—
ReactantHCID 57933915HCID 57933915—
ProductHCID 57934525HCID 5793452536.4%

Reaction Steps

Synthesized from pivalic acid (S)-6-[2-(ethoxycarbonylmethylamino)-4,5-dimethoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-yl ester (90 mg) and 4-(4-carboxyphenyl)piperidine-1-carboxylic acid tert-butyl ester (88 mg) according to an analogous synthetic method to the above-mentioned Preparation Example 86 and Example 337, the title compound (37 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-21aacc164b5a4369a79361db43352ad3
Source noteuspto-grants-2013_03