HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester → HCID 57934545, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester | HCID 22492859 | — |
| Reactant | HCID 57934371 | HCID 57934371 | — |
| Product | HCID 57934545 | HCID 57934545 | 56.7% |
Reaction Steps
Synthesized from pivalic acid (R)-6-[2-(ethoxycarbonylmethylamino)-4,5-dimethoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-yl ester (39 mg) and 4-(4-carboxyphenyl)piperidine-1-carboxylic acid tert-butyl ester (38 mg) according to an analogous synthetic method to the above-mentioned Preparation Example 86 and Example 337, the title compound (25 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-6f18d3ab33344798a544c187ee2215f4 |
| Source note | uspto-grants-2013_03 |