Furfurylamine → HCID 178518100, compound

Participants

Reaction Steps

To the reaction flask with 40 g cytosine (0.36 mol), 190 ml furfurylamine (6 mol) (FIG. 1 IV and V), the same amount of water and 5.67 g catalyst ammonium chloride (0.3 mol) was added. The mixture was heated till boiling within 48-96 h. After cooling, the mixture was extracted with dichloromethane (ca. 300 ml). The organic layer was filtered to isolate the product. The raw product was crystallized and 61.196 g of pure product was obtained with yield 89%.

Provenance & Evidence