HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)aniline → HCID 58494233, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)aniline | HCID 7375 | — |
| Reactant | Ethyl 4-chloro-6-methyl-2-(methylsulfanyl)pyrimidine-5-carboxylate | HCID 22225416 | — |
| Product | HCID 58494233 | HCID 58494233 | 97.5% |
Reaction Steps
The title compound; (MS m/z: 372.2 (M+H)+) was prepared as described in example 1d by starting from ethyl 4-chloro-6-methyl-2-(methyl thio)pyrimidine-5-carboxylate (1.2 g, 4.86 mmol) and 3-(trifluoromethyl)aniline (611 uL, 4.86 mmol) and continuing until the reaction yielded dark brown solids (ethyl 4-methyl-2-(methylthio)-6-(3-(trifluoromethyl)phenylamino)pyrimidine-5-carboxylate (1.76 g, 97.4%)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404677B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-70101521adf249ae9a96c2c79fd4730d |
| Source note | uspto-grants-2013_03 |