HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenamine, 3,5-bis(trifluoromethyl)- → HCID 86658933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenamine, 3,5-bis(trifluoromethyl)- | HCID 9480 | — |
| Reactant | Ethyl 4-chloro-6-methyl-2-(methylsulfanyl)pyrimidine-5-carboxylate | HCID 22225416 | — |
| Product | HCID 86658933 | HCID 86658933 | 71.7% |
Reaction Steps
The title compound was prepared as described in Example 1d by starting from ethyl 4-chloro-6-methyl-2-(methyl thio)pyrimidine-5-carboxylate (1.2 g, 4.86 mmol) and 3,5-bis(trifluoromethyl)aniline (777 uL, 4.86 mmol) and continuing until the reaction yielded the brown solids, title compound ethyl 4-(3,5-bis(trifluoromethyl)phenylamino)-6-methyl-2-(methylthio)pyrimidine-5-carboxylate (1.53 g, 70.2%). MS m/z: 440.1 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404677B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-6b9c1fe165f948c6b44427a4bbb23663 |
| Source note | uspto-grants-2013_03 |