HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 25255382, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 16771415 | HCID 16771415 | — |
| Reactant | 5-fluoro-N'-hydroxy-2-methoxybenzenecarboximidamide | HCID 72336823 | — |
| Product | HCID 25255382 | HCID 25255382 | — |
Reaction Steps
Oxalyl chloride (130 μL; 1.54 mmol; 3 eq.), Intermediate 38 (120 mg; 0.51 mmol; 1 eq.), Intermediate 23 (94 mg; 0.51 mmol, 1 eq.) and DIEA (260 μL; 1.54 mmol; 3 eq.) were reacted according to general procedure 2. Purification by column chromatography (c-hexane/ethyl acetate, 50/50) afforded the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404676B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-16c4b9309d0f4005ac74ce36b6a23c51 |
| Source note | uspto-grants-2013_03 |