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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950943Generated: October 26, 2026

1,5-Dibromopentane → cis-2-Methoxy-N-(2-piperidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1950943

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,5-DibromopentaneHCID 8100—
Reactantcis-N-(2-Amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamideHCID 58062915—
Productcis-2-Methoxy-N-(2-piperidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamideHCID 58062884—

Reaction Steps

The title compound, white solid, MS: m/e=453.2 [(M+H)+], was prepared in accordance with the general method of example 10 from cis-N-(2-amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide (intermediate H) and 1,5-dibromopentane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-bd5678654c024ad6a0ea2356f7e6bfd8
Source noteuspto-grants-2013_03