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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950945Generated: October 25, 2026

Cyclobutanone → cis-N-(2-Cyclobutylamino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1950945

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanoneHCID 14496—
Reactantcis-N-(2-Amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamideHCID 58062915—
Productcis-N-(2-Cyclobutylamino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamideHCID 58062857—

Reaction Steps

The title compound, off-white solid, MS: m/e=439.2 [(M+H)+], was prepared in accordance with the general method of example 11 from cis-N-(2-amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide (intermediate H) and cyclobutanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-fff984b33f5a42b6bb51eccda7840f83
Source noteuspto-grants-2013_03