Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950946Generated: October 26, 2026

Cyclobutanone → cis-N-(2-Cyclobutylamino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1950946

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanoneHCID 14496—
Reactantcis-N-(2-Amino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 58062914—
Productcis-N-(2-Cyclobutylamino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 51000594—

Reaction Steps

The title compound, colorless amorphous, MS: m/e=417.2 [(M+H)+], was prepared in accordance with the general method of example 11 from cis-N-(2-amino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate I) and cyclobutanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-d4c0f8c390b943c4a2d6020a3e3fc633
Source noteuspto-grants-2013_03