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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950960Generated: October 25, 2026

Cyclopentanone → N-((1RS,2SR)-2-Cyclopentylamino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1950960

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanoneHCID 8452—
Reactantcis-N-(2-Amino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 58062914—
ProductN-((1RS,2SR)-2-Cyclopentylamino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 51000675—

Reaction Steps

The title compound, light yellow solid, MS: m/e=431.3 [(M+H)+], was prepared in accordance with the general method of example 11 from cis-N-(2-amino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate I) and cyclopentanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-ad916108a9564759a807bb82aa426d25
Source noteuspto-grants-2013_03