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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950972Generated: November 1, 2026

Cyclopentanone → N-((1RS,2SR)-2-Cyclopentylamino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1950972

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanoneHCID 8452—
ReactantN-((1RS,2SR)-2-Amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 66681196—
ProductN-((1RS,2SR)-2-Cyclopentylamino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 51000991—

Reaction Steps

The title compound, off-white solid, MS: m/e=417.3 [(M+H)+], was prepared in accordance with the general method of example 11 from N-((1RS,2SR)-2-amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate O) and cyclopentanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-4f6ab489ff89411bb063c01bedc3df8e
Source noteuspto-grants-2013_03