HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Bis(trifluoromethyl)benzoic acid → N-(cis-2-Pyrrolidin-1-yl-cyclopentyl)-2,4-bis-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Bis(trifluoromethyl)benzoic acid | HCID 141752 | — |
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Product | N-(cis-2-Pyrrolidin-1-yl-cyclopentyl)-2,4-bis-trifluoromethyl-benzamide | HCID 58063002 | — |
Reaction Steps
The title compound, yellow solid, MS: m/e=395.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2,4-bis(trifluoromethyl)benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404673B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-7ce65d67c1ca44959b47c74e66c98062 |
| Source note | uspto-grants-2013_03 |