HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 2-(methylthio)-4-(trifluoromethyl)- → cis-2-Methylsulfanyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 2-(methylthio)-4-(trifluoromethyl)- | HCID 11085762 | — |
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Product | cis-2-Methylsulfanyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide | HCID 58062856 | — |
Reaction Steps
The title compound, light yellow oil, MS: m/e=372.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-methylsulfanyl-4-trifluoromethyl-benzoic acid (intermediate C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404673B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-ff10de505024478a8b1b65c5dc5e1f51 |
| Source note | uspto-grants-2013_03 |