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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950981Generated: October 31, 2026

4-Chloro-2-methylbenzoic acid → cis-4-Chloro-2-methyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-benzamide

https://huagongshe.com/reaction/1950981

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-methylbenzoic acidHCID 348269—
Reactantcis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
Productcis-4-Chloro-2-methyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-benzamideHCID 66681577—

Reaction Steps

The title compound, light brown viscous oil, MS: m/e=307.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 4-chloro-2-methylbenzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-6cf0a0d4db5a4b7c923c805c56dfbae2
Source noteuspto-grants-2013_03