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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950982Generated: October 25, 2026

cis-2-Pyrrolidin-1-yl-cyclopentylamine → cis-2-Ethyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1950982

Reaction equation

Participants

RoleNameHCIDCharge
Reactantcis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
Reactant2-Ethyl-4-(trifluoromethyl)benzoic acidHCID 53406012—
Productcis-2-Ethyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamideHCID 51001150—

Reaction Steps

The title compound, white solid, MS: m/e=355.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-ethyl-4-(trifluoromethyl)-benzoic acid (CAS 854531-63-8).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-9d3b69e115e04c1c8f94710c14c6f23a
Source noteuspto-grants-2013_03