Cyclopentanone → HCID 51001151, compound

HRID 1950987Notes

Reaction equation

HRID 1950987 reaction equation
[NH2:1][C@H:2]1[CH2:6][CH2:5][CH2:4][C@H:3]1[NH:7][C:8](=[O:21])[C:9]1[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[CH:11][C:10]=1[CH2:19][CH3:20].[C:22]1(=O)[CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH:22]1([NH:1][C@H:2]2[CH2:6][CH2:5][CH2:4][C@H:3]2[NH:7][C:8](=[O:21])[C:9]2[CH:14]=[CH:13][C:12]([C:15]([F:17])([F:18])[F:16])=[CH:11][C:10]=2[CH2:19][CH3:20])[CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 8452CyclopentanoneHCID 66680754HCID 66680754, compound2×

Product 1

HCID 51001151HCID 51001151, compound

Procedure

The title compound, white solid, MS: m/e=369.2 [(M+H)+], was prepared in accordance with the general method of example 11 from cis-N-(2-Amino-cyclopentyl)-2-ethyl-4-trifluoromethyl-benzamide (intermediate S) and cyclopentanone.

Sources & evidence

ORD record
ord-f1f9ab6f8740496d92ffcdd1d8e90a14
Source dataset
uspto-grants-2013_03
Patent number
US08404673B2

Reaction notes

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