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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950990Generated: October 31, 2026

2-Ethyl-6-methylbenzoic acid → cis-2-Ethyl-6-methyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-benzamide

https://huagongshe.com/reaction/1950990

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Ethyl-6-methylbenzoic acidHCID 12044229—
Reactantcis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
Productcis-2-Ethyl-6-methyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-benzamideHCID 51001153—

Reaction Steps

The title compound, white solid, MS: m/e=301.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-ethyl-6-methylbenzoic acid (CAS 106976-50-5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-27d54de5ff9d4c8ea580d48abe1a2272
Source noteuspto-grants-2013_03