HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-2-Pyrrolidin-1-yl-cyclopentylamine → 5-Trifluoromethyl-biphenyl-2-carboxylic acid ((1SR,2RS)-2-pyrrolidin-1-yl-cyclopentyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Reactant | 5-(Trifluoromethyl)biphenyl-2-carboxylic acid | HCID 46315197 | — |
| Product | 5-Trifluoromethyl-biphenyl-2-carboxylic acid ((1SR,2RS)-2-pyrrolidin-1-yl-cyclopentyl)-amide | HCID 66681902 | — |
Reaction Steps
The title compound, off-white oil, MS: m/e=403.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 5-trifluoromethyl-biphenyl-2-carboxylic acid (intermediate AI).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404673B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-7a50336e3b0142f680b8a58e19c3121c |
| Source note | uspto-grants-2013_03 |