HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-2-Pyrrolidin-1-yl-cyclopentylamine → 2-Cyclobutyl-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Reactant | 2-Cyclobutyl-4-trifluoromethyl-benzoic acid | HCID 59438432 | — |
| Product | 2-Cyclobutyl-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide | HCID 66681772 | — |
Reaction Steps
The title compound, light orange solid, MS: m/e=381.4 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-cyclobutyl-4-trifluoromethyl-benzoic acid (intermediate AP).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404673B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-c9d8471913624186b945c83b8ce5d283 |
| Source note | uspto-grants-2013_03 |