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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1951014Generated: October 31, 2026

cis-2-Pyrrolidin-1-yl-cyclopentylamine → 2-Ethyl-6-methoxy-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1951014

Reaction equation

Participants

RoleNameHCIDCharge
Reactantcis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
Reactant2-Ethyl-6-methoxy-4-trifluoromethyl-benzoic acidHCID 58167768—
Product2-Ethyl-6-methoxy-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamideHCID 51001331—

Reaction Steps

The title compound, light yellow oil, MS: m/e=385.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-ethyl-6-methoxy-4-trifluoromethyl-benzoic acid (intermediate AR).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-e769236992d74b68ba9e8cf3e346bef6
Source noteuspto-grants-2013_03