HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,1,3-Benzoxadiazole-5-carbonyl chloride → N-(Tetrahydro-2H-pyran-3-yl)-[2,1,3]-benzoxadiazole-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,1,3-Benzoxadiazole-5-carbonyl chloride | HCID 2735453 | — |
| Reactant | Oxan-3-amine hydrochloride | HCID 46735995 | — |
| Product | N-(Tetrahydro-2H-pyran-3-yl)-[2,1,3]-benzoxadiazole-5-carboxamide | HCID 25104168 | — |
Reaction Steps
N-(Tetrahydro-2H-pyran-3-yl)-[2,1,3]-benzoxadiazole-5-carboxamide was prepared from 3-aminotetrahydropyran hydrochloride and [2,1,3]-benzoxadiazole-5-carbonylchloride using the procedure described for Example 7. Mp=204-205° C., 1H NMR (300 MHz, CDCl3) δ 8.24-8.10 (m, 1H), 7.93 (dd, 1H, J=9.0 and 0.9 Hz); 7.84 (dd, 1H, J=9.0 and 1.2 Hz); 6.70-6.60 (m, NH, 1H); 4.24-4.22 (m, 1H), 3.86-3.60 (m, 4H) and 1.97-1.61 ppm (m, 4H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404682B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-06ad238dc4054152ae7e478aaef5d098 |
| Source note | uspto-grants-2013_03 |