Pyrrolidine → HCID 67025799, compound

Participants

Reaction Steps

In analogy to the procedure described for the synthesis of pyrrolidine intermediate VIII-1 (step b), the title compound (3RS,4SR)-1-benzyl-4-(4-chloro-2-methyl-phenyl)-pyrrolidin-3-ylamine was prepared from (3SR,4RS)-1-benzyl-3-(4-chloro-2-methyl-phenyl)-4-nitro-pyrrolidine instead of (3SR,4RS)-1-benzyl-3-(3,4-dichloro-phenyl)-4-nitro-pyrrolidine and was obtained as a light brown foam. MS m/e: 301.2 [M+H]+.

Provenance & Evidence