HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-{3-[4-Methyl-5-(2-morpholin-4-yl-pyridin-4-yl)-thiazol-2-yl]-ureido}-propionic acid ethyl ester → 3-[3-(4-Methyl-5-pyridin-4-yl-thiazol-2-yl)-ureido]-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-{3-[4-Methyl-5-(2-morpholin-4-yl-pyridin-4-yl)-thiazol-2-yl]-ureido}-propionic acid ethyl ester | HCID 11247129 | — |
| Reactant | [3-(4-Methyl-5-pyridin-4-yl-thiazol-2-yl)-ureido]-acetic acid ethyl ester | HCID 11415948 | — |
| Product | 3-[3-(4-Methyl-5-pyridin-4-yl-thiazol-2-yl)-ureido]-propionic acid ethyl ester | HCID 11416363 | — |
Reaction Steps
This compound is prepared by an analogous procedure to 3-{3-[4-Methyl-5-(2-morpholin-4-yl-pyridin-4-yl)-thiazol-2-yl]-ureido}-propionic acid ethyl ester (Example 14) by replacing 4-Methyl-5-(2-morpholin-4-yl-pyridin-4-yl)-thiazol-2-ylamine hydrobromide (13b) with 4-methyl-5-pyridin-4-yl-thiazol-2-ylamine (see Example 16 for reference).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404684B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-db1c140c7b3346bd82afd42fa84d251a |
| Source note | uspto-grants-2013_03 |