HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → 5-(2,6-Dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 5-(2,6-Dimethyl-pyridin-4-yl)4-methyl-thiazol-2-ylamine hydrobromide | HCID 86610332 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-(2,6-Dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-ylamine | HCID 45097637 | — |
Reaction Steps
To a stirred solution of 5-(2,6-Dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-ylamine hydrobromide (3.29 g, 11 mmol) in methanol (30 ml) is added sodium methoxide (2 ml of a 30% solution in methanol, 11 mmol). The resulting mixture is filtered through Celite™ filter material and concentrated in vacuo to yield the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404684B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-53d76a972a314913863a7893bfa6fb95 |
| Source note | uspto-grants-2013_03 |