5-(2,6-Dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-ylamine → Imidazole-1-carboxylic acid [5-(2,6-dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-yl]-amide

HRID 1951188Notes

Reaction equation

HRID 1951188 reaction equation
CC1N=C(N[C:14]([N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)=[O:15])SC=1C1C=CN=CC=1.[CH3:21][C:22]1[CH:27]=[C:26]([C:28]2[S:32][C:31]([NH2:33])=[N:30][C:29]=2[CH3:34])[CH:25]=[C:24]([CH3:35])[N:23]=1>>[CH3:21][C:22]1[CH:27]=[C:26]([C:28]2[S:32][C:31]([NH:33][C:14]([N:16]3[CH:20]=[CH:19][N:18]=[CH:17]3)=[O:15])=[N:30][C:29]=2[CH3:34])[CH:25]=[C:24]([CH3:35])[N:23]=1

Participants

3

Reactant 2

HCID 450976375-(2,6-Dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-ylamineHCID 86610330Imidazole-1-carboxylic acid (4-methyl-5-pyridin-4-yl-thiazol-2-yl)-amide

Product 1

HCID 86610333Imidazole-1-carboxylic acid [5-(2,6-dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-yl]-amide

Procedure

The titled compound is prepared by an analogous procedure to imidazole-1-carboxylic acid (4-methyl-5-pyridin-4-yl-thiazol-2-yl)-amide (example 18a) by replacing 4-methyl-5-pyridin-4-yl-thiazol-2-ylamine with 5-(2,6-Dimethyl-pyridin-4-yl)-4-methyl-thiazol-2-ylamine.

Sources & evidence

ORD record
ord-e629457ad0f24a4a8b4551825259342c
Source dataset
uspto-grants-2013_03
Patent number
US08404684B2

Reaction notes

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