HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpropanimidamide hydrochloride → N-[5-(2-Isopropyl-pyrimidin-4-yl)-4-methyl-thiazol-2-yl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpropanimidamide hydrochloride | HCID 2782053 | — |
| Reactant | N-[4-Methyl-5-(2-morpholin-4-yl-pyrimidin-4-yl)-thiazol-2-yl]-acetamide | HCID 86610334 | — |
| Product | N-[5-(2-Isopropyl-pyrimidin-4-yl)-4-methyl-thiazol-2-yl]-acetamide | HCID 11265855 | — |
Reaction Steps
The titled compound is prepared by an analogous procedure to N-[4-Methyl-5-(2-morpholin-4-yl-pyrimidin-4-yl)-thiazol-2-yl]-acetamide (25e) by replacing morpholinoformamidine hydrobromide (part 25c) with isobutyramidine hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404684B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-f0f354ede1494d3185fb71d5051bfd60 |
| Source note | uspto-grants-2013_03 |