4-Methyl-2-(methylsulfanyl)pyrimidine → 4-Methyl-5-(2-(methylthio)pyrimidin-4-yl)thiazol-2-amine

HRID 1951207Notes

Reaction equation

HRID 1951207 reaction equation
[CH3:1][C:2]1C=C(C)[N:5]=[C:4]([SH:9])[N:3]=1.[CH3:10][C:11]1[CH:16]=[CH:15][N:14]=[C:13]([S:17][CH3:18])[N:12]=1>>[CH3:1][C:2]1[N:3]=[C:4]([NH2:5])[S:9][C:10]=1[C:11]1[CH:16]=[CH:15][N:14]=[C:13]([S:17][CH3:18])[N:12]=1

Participants

3

Reactant 2

HCID 8212614-Methyl-2-(methylsulfanyl)pyrimidineHCID 1784266324,6-dimethylpyrimidine-2-thiol

Product 1

HCID 575066564-Methyl-5-(2-(methylthio)pyrimidin-4-yl)thiazol-2-amine

Procedure

This material is prepared by the procedure outlined for intermediate AC, replacing 4,6-dimethyl-pyrimidine-2-thiol in the first step (AC1) with 4-methyl-2-methylsulfanyl-pyrimidine.

Workup

  1. customThis material is prepared by the procedure

Sources & evidence

ORD record
ord-73c9f1fa36354f09b803058e9e592747
Source dataset
uspto-grants-2013_03
Patent number
US08404684B2

Reaction notes

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