HCID 11473512, compound → HCID 11402779, compound

HRID 1951239Notes

Reaction equation

HRID 1951239 reaction equation
[CH3:1][C:2]1[N:7]=[C:6]([C:8]2[S:12][C:11]([NH2:13])=[N:10][C:9]=2[CH3:14])[CH:5]=[C:4]([CH3:15])[N:3]=1.CN(C)CCN(C)C1N=C(C2SC(N[C:33](=[O:35])[CH3:34])=NC=2C)C=C(C)N=1>>[CH3:1][C:2]1[N:7]=[C:6]([C:8]2[S:12][C:11]([NH:13][C:33](=[O:35])[CH3:34])=[N:10][C:9]=2[CH3:14])[CH:5]=[C:4]([CH3:15])[N:3]=1

Participants

3

Reactant 2

HCID 11473512HCID 11473512, compoundHCID 45097681HCID 45097681, compound

Product 1

HCID 11402779HCID 11402779, compound

Procedure

This is prepared by acylating 5-(2,6-dimethyl-pyrimidin-4-yl)-4-methyl-thiazol-2-ylamine (intermediate AF) using the procedure described for N-(5-{2-[(2-dimethylamino-ethyl)-methyl-amino]-6-methyl-pyrimidin-4-yl}-4-methyl-thiazol-2-yl)-acetamide (Example 39, step 2).

Workup

  1. customThis is prepared

Sources & evidence

ORD record
ord-5456cd0032f7419a9c9c47caa53ac40d
Source dataset
uspto-grants-2013_03
Patent number
US08404684B2

Reaction notes

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