HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Bromide → Imidazo[1,2-a]pyridin-8-ylmethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Bromide | HCID 253877 | — |
| Reactant | Ethyl imidazo[1,2-a]pyridine-8-carboxylate | HCID 10867135 | — |
| Product | Imidazo[1,2-a]pyridin-8-ylmethanol | HCID 11029987 | — |
Reaction Steps
From 2a (yield: 82%); mp 177-479° C.; IR (KBr) 1505, 1300, 1140, 1015, 780, 735 cm−1; 1H NMR (400 MHz, CDCl3) δ 4.99 (s, 2H), 5.65 (s, 1H), 6.78 (t, 1H, J=6.5 Hz), 7.17 (d, 1H, J=6.5 Hz), 7.27 (s, 1H), 7.59 (s, 1H), 8.08 (d, 1H, J=6.5 Hz); 13C NMR (100 MHz, CDCl3) δ 58.5, 112.5, 112.7, 121.6, 125.0, 130.0, 132.7, 144.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404707B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-98c5176fe37f42c0ad0d59fec695085f |
| Source note | uspto-grants-2013_03 |