HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazo[1,2-a]pyridine-8-carboxylic acid, 2-methyl-, ethyl ester → 2-Methylimidazo[1,2-a]pyridine-8-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazo[1,2-a]pyridine-8-carboxylic acid, 2-methyl-, ethyl ester | HCID 18983836 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 2-Methylimidazo[1,2-a]pyridine-8-methanol | HCID 13900330 | — |
Reaction Steps
From 2b (yield: 42%) as an oil; IR (CCl4) 2960, 1499, 1366, 1324 cm−1; 1H NMR (400 MHz, CDCl3) δ 2.36 (s, 3H), 4.96 (s, 2H), 6.64 (t, 1H, J=7 Hz), 7.11 (d, 1H, J=7 Hz), 7.25 (s, 1H), 7.88 (d, 1H, J=7 Hz); 13C NMR (100 MHz, CDCl3) δ 14.0, 60.8, 109.7, 111.9, 121.5, 124.1, 129.2, 142.2, 143.6; MS m/z 162 (M+, 36), 161 (100), 133 (55), 132 (46), 78 (31), 51 (16).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404707B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-88d50f9d48964cd5ad66e3dbf8713ce3 |
| Source note | uspto-grants-2013_03 |