HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Bromide → Imidazo(1,2-a)pyridine-8-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Bromide | HCID 253877 | — |
| Reactant | Imidazo[1,2-a]pyridin-8-ylmethanol | HCID 11029987 | — |
| Product | Imidazo(1,2-a)pyridine-8-carbaldehyde | HCID 10997174 | 85% |
Reaction Steps
From 3a, reaction time 1.5 h (yield: 85%); mp 137-139° C. (in Yamanaka, M. and al. Chem. Pharm. Bull. 1991, 39, 1556-1567: 103-104° C.); IR (KBr) 1675, 1450, 1320, 1175 cm−1, 1H NMR (400 MHz, CDCl3) δ 7.01 (t, 1H, J=6.5 Hz), 7.75 (s, 1H), 7.82 (s, 1H), 7.86 (d, 1H, J=6.5 Hz), 8.42 (d, 1H, J=6.5 Hz), 10.8 (s, 1H); 13C NMR (CDCl3) δ 111.9, 113.3, 124.2, 126.9, 130.7, 134.9, 143.8, 188.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404707B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-940b9fd095c747dcb937e49e196c590d |
| Source note | uspto-grants-2013_03 |