HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Bromide → 2-(1-Methylethyl)imidazo[1,2-a]pyridine-8-carboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Bromide | HCID 253877 | — |
| Reactant | HCID 46205730 | HCID 46205730 | — |
| Product | 2-(1-Methylethyl)imidazo[1,2-a]pyridine-8-carboxaldehyde | HCID 46206055 | 57% |
Reaction Steps
From 3f: reaction time 15 h (yield: 57%); mp 70-72° C.; IR (KBr) 1669, 1540, 1500 cm−1; 1H NMR (400 MHz, CDCl3) δ 1.39 (d, 6H, J=7 Hz), 3.20 (sept, 1H, J=7 Hz), 6.90 (t, 1H, J=7 Hz), 7.46 (s, 1H), 7.77 (d, 1H, J=7 Hz), 8.30 (d, 1H, J=7 Hz), 10.79 (s, 1H); 13C NMR (100 MHz, CDCl3) δ 22.4, 28.6, 107.9, 111.2, 123.4, 125.5, 130.2, 143.7, 156.0, 189.2; MS m/z 188 (M+, 60), 173 (56), 160 (100), 145 (26), 78 (21).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404707B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-d68737e8b3b24db094fba638f5f72b0c |
| Source note | uspto-grants-2013_03 |