HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Bromide → 3-Bromo-2-methylimidazo[1,2-a]pyridine-8-carboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Bromide | HCID 253877 | — |
| Reactant | 2-Methylimidazo[1,2-a]pyridine-8-carbaldehyde | HCID 13900241 | — |
| Product | 3-Bromo-2-methylimidazo[1,2-a]pyridine-8-carboxaldehyde | HCID 46206058 | — |
Reaction Steps
From 4b (yield: 68%); mp 137-139° C.; IR (KBr) 1695, 1541 cm−1; 1H NMR (400 MHz, CDCl3) δ 2.55 (s, 3H), 7.08 (t, 1H, J=7 Hz), 7.87 (d, 1H, J=7 Hz), 8.30 (d, 1H, J=7 Hz), 10.72 (s, 1H); 13C NMR (100 MHz, CDCl3) δ 13.7, 94.6, 112.3, 123.3, 126.8, 128.4, 143.6, 143.7, 188.3; MS m/z 240 (M++2, 66), 238 (M+, 67), 212 (98), 210 (100), 131 (77), 104 (73), 78 (33), 51 (40).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404707B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-8b0148ed1a364665bc05789e23ea643f |
| Source note | uspto-grants-2013_03 |