2-Thiophenesulfonyl chloride → 3-Acetyl-2-methyl-4-(2-methyl-4-oxo-4H-chromen-8-yl)-1,4-dihydro-1,6-naphthyridin-5-yl thiophene-2-sulfonate

Participants

Reaction Steps

The title compound is prepared in analogy to example 10 from 50 mg (0.13 mmol) of 3-acetyl-2-methyl-4-(2-methyl-4-oxo-4H-chromen-8-yl)-4,6-dihydro-1,6-naphthyridin-5(1H)-one and 28 mg (0.15 mmol) of thiophene-2-sulfonyl chloride. 57 mg (81% of theory) of the product are obtained as a pale yellow solid.

Provenance & Evidence