HCID 57465372, compound → HCID 57465373, compound

Participants

Reaction Steps

to a suspension of 5-methyl-2-(4-nitrophenyl)-4-phenyloxazole (1.20 g, 4.3 mmol) in acetic acid at room temperature was added all at once zinc dust (0.59 ml, 64 mmol). An exotherm developed. The mixture was stirred vigorously for 90 minutes then filtered. The filtrate was concentrated under reduced pressure, diluted with toluene then concentrated under reduced pressure to afford a yellow oily solid (1.1 g, quant.). ESI+ m/z=251.1 [MH]+.

Provenance & Evidence